CaM Kinase 1β, active

Background Information:

CaM Kinase 1b (Calcium/calmodulin-dependent protein kinase 1b) is a serine/threonine protein kinase that belongs to the CaM Kinase family of kinases. It is a key mediator of intracellular calcium signaling and is involved in the regulation of a wide range of cellular processes, including synaptic plasticity, learning and memory, and gene expression. In the brain, CaM Kinase 1b is particularly important in the regulation of synaptic plasticity and learning and memory. It has been shown to play a role in long-term potentiation (LTP), a process by which synaptic strength is enhanced in response to repeated stimulation, and is necessary for certain forms of learning and memory. CaM Kinase 1b is also involved in the regulation of gene expression, and has been implicated in the development and progression of several diseases, including cancer, cardiovascular disease, and neurological disorders.

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

CaMK1b

Accession Number:

XM_011531113.1

UniProt Number:

Q6P2M8

Gene Name:

PNCK

Gene ID:

139728

Gene Aliases:

MGC45419|CaMK1b

Target Species:

Human