| Biological Information | |
|---|---|
| Background Information: | Camptothecin is a cytotoxic quinoline plant alkaloid that inhibits DNA and RNA synthesis by specifically inhibiting the DNA topoisomerase I enzyme. Shows great anti-tumor potential in the clinic by inducing DNA breaks and apoptosis, but shows in vivo cytotoxicity. Derivatives of camptothecin have been developed and are used in chemotherapy, such as toptecan and irinotecan. An agonist of the p53 pathway and inhibitor of TOP1. Provided as 25 mg of dry powder. |
| Target Name: | Camptothecin |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at 2-8°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Camptothecin
Camptothecin is an agonist for the p53 pathway and an inhibitor of TOP1. This product is provided as 25 mg of dry powder.
Datasheets
92-1146 Datasheet
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