| Biological Information | |
|---|---|
| Background Information: | DYRK3 (Dual-specificity Tyrosine Phosphorylation-Regulated Kinase 3) is a serine/threonine protein kinase that belongs to the DYRK (dual-specificity tyrosine-phosphorylation regulated kinase) family of kinases. It is involved in a variety of cellular processes, including regulation of the cell cycle, DNA damage response, and apoptosis.
Research has suggested that DYRK3 plays a role in several diseases, including cancer, neurodegenerative diseases, and viral infections. In cancer, DYRK3 has been shown to contribute to tumor growth and survival, and inhibition of DYRK3 has been suggested as a potential cancer therapy. In neurodegenerative diseases, DYRK3 has been implicated in the regulation of neuronal survival and degeneration, and alterations in DYRK3 expression and activity have been observed in the brains of patients with Alzheimer's disease and Parkinson's disease. Additionally, inhibition of DYRK3 has been suggested as a potential therapeutic strategy for viral infections. |
| Target Class: | Kinase |
| Accession Number: | NM_003582.2 |
| Target Name: | DYRK3 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
DYRK3, active
N-terminal GST-tagged and C-terminal 6His tagged, recombinant, human DYRK3 full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography.
Datasheets
15-002x Datasheet
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