| Biological Information | |
|---|---|
| Background Information: | Geldanamycin is an antibiotic and a potent inhibitor of the heat shock protein 90 (Hsp90) protein (KD=1.2uM), binding its ATP site and inhibiting its chaperone activity. Induces selective degradation of mutated versions of v-Src, Bcr-Abl, Raf, p53, and steroid receptors in tumor cells via Hsp90 inhibition. Affects multiple cellular processes, including gene expression, cell proliferation, apoptosis, and angiogenesis. Provided as 1 mg of dry powder. |
| Target Name: | Geldanamycin |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at -20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Geldanamycin
Geldanamycin is an inhibitor of Hsp90. This product is provided as 1 mg of dry powder.
Datasheets
92-1235 Datasheet
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