Biological Information
Background Information:
Murine Complement Component 5a (C5a) is a pro-inflammatory protein fragment anaphylatoxin, and is cleaved by C5-convertase from complement component C5. Acting as an agonist for C5AR1 and C5AR2 on macrophages, neutrophils, and endothelial cells, C5a is a strong chemoattractant in stimulating an inflammatory response, and is recruited with the complement system network during an immune response to tissue damage or foreign objects. It is widely involved in many forms of inflammatory diseases, including asthma, ischemia-reperfusion injury, acute lung injury, and sepsis. Provided as 25 μg of dry powder alongside reconstitution buffer.
Target Species:
Mouse
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®