| Biological Information | |
|---|---|
| Background Information: | U-18666A is a small molecule inhibitor of cholesterol transport from endosomes/lysosomes to the endoplasmic reticulum in a variety of cell types, including macrophages and sympathetic neurons. Also weakly inhibits hedgehog signaling. Implicated in multiple diseases including Neimann-Pick disease type C (NPC), Alzheimer's, cataracts, and atherosclerosis. |
| Target Name: | U-18666A |
| Usage | |
| Product Type: | Control Ligands & Inhibitors |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at ≤-20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
U-18666A
U-18666A is a small molecule inhibitor of cholesterol transport from endosomes/lysosomes to the endoplasmic reticulum in a variety of cell types, including macrophages and sympathetic neurons.
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