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ACK1, active

/products/proteins/14-756
ACK1, active

/products/proteins/14-756m
tyrosine kinase, non-receptor, 2 (TNK2)
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. ...
/target-data-sheets/kinase/tnk2 2/12/2015 9:48:31 PM
High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.
Selective protein kinase inhibitors have only been developed against a small number of kinase targets. Here we demonstrate that "high-throughput kinase profiling" is an efficient method for the discovery of lead compounds for established as well as unexplored kinase targets. W...
/tools-resources/publications-references/publications/high-throughput-kinase-profiling-a-more-efficient 10/3/2012 5:51:27 PM
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