/products/proteins/14-835
/products/proteins/14-835m
/products/proteins/14-511
/products/proteins/14-511m
/products/proteins/14-911
/products/proteins/14-911m
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centros...
/target-data-sheets/kinase/aurkc
2/12/2015 9:46:16 PM
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromsomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and m...
/target-data-sheets/kinase/aurkb
2/12/2015 9:46:16 PM
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle ...
/target-data-sheets/kinase/aurka
2/12/2015 9:46:15 PM
To realize the full potential of targeted protein kinase inhibitors for the treatment of cancer, it is important to address the emergence of drug resistance in treated patients. Mutant forms of BCR-ABL, KIT, and the EGF receptor (EGFR) have been found that confer resistance to...
/tools-resources/publications-references/publications/inhibition-of-drug-resistant-mutants-of-abl-kit-an
10/3/2012 5:51:26 PM
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