The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endo...
/target-data-sheets/kinase/ern1
2/12/2015 9:46:57 PM
/products/proteins/14-930
/products/proteins/14-930m
/products/proteins/16-054
/products/proteins/16-054m
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of t...
/target-data-sheets/pathways/xbp1
2/12/2015 9:46:03 PM