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JAK3, active

/products/proteins/14-629
JAK3, active

/products/proteins/14-629m
Janus kinase 3 (JAK3)
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via t...
/target-data-sheets/kinase/jak3 2/12/2015 9:44:45 PM
PathHunter® eXpress JAK3 Activity Assay

/products/assay/jak3-activity-assay-93-0796e3cp16m
PathHunter® eXpress JAK3 Activity Assay

/products/assay/jak3-activity-assay-93-0796e3cp16l
PathHunter® U2OS JAK3 Activity Assay

/products/cell-line/u2os-jak3-activity-assay-93-0796c3
Janus kinase 3 (JAK3(JH1domain-catalytic))
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via t...
/target-data-sheets/kinase/jak3(jh1domain-catalytic) 2/12/2015 9:47:16 PM
Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550).
Here, we examine the significance that stereochemistry plays within the clinically relevant Janus kinase 3 (Jak3) inhibitor 1 (CP-690,550). A synthesis of all four enantiopure stereoisomers of the drug was carried out and an examination of each compound revealed that only the ...
/tools-resources/publications-references/publications/examining-the-chirality-conformation-and-selective 10/3/2012 5:51:35 PM
Product Specific Landing Page
Product Name Catalog No. Size Price Qty   PathHunter® select U2OS Cell Culture Kit-L 92-0018GL3 50ml $50.00 1 Add to Cart PathHunter® Cell Planting 16 Reagent 93-0563R16A 250ml ...
/targets/signaling-pathways/gene-specific-landing-page/product-specific-landing-page 9/7/2012 8:52:53 PM
Kinases - RTK & CTK
Applications Eurofins DiscoverX offers a variety of cell-based assays in the form of cell lines and ready-to-use eXpress kits for analyzing kinase functional activity, dimerization, characterization, and screening. Please contact custom assay development for additional assay...
/technologies-platforms/enzyme-fragment-complementation-technology/cell-based-efc-assays/protein-protein-interactions/kinases-cell-based-(rtk-ctk) 5/31/2017 9:09:38 PM
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