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Mer, active

/products/proteins/14-728
Mer, active

/products/proteins/14-728m
c-mer proto-oncogene tyrosine kinase (MERTK)
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disr...
/target-data-sheets/kinase/mertk 2/12/2015 9:47:31 PM
PathHunter® U2OS MERTK Functional Assay

/products/cell-line/u2os-mertk-functional-assay-93-1151c3
G protein-coupled estrogen receptor 1 (GPER)
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisp...
/target-data-sheets/gpcr/gpr30 2/12/2015 9:44:20 PM
cAMP Hunter™ Follitropin Alfa Bioassay Kit

/products/assay/follitropin-alfa-bioassay-kit-95-0119y2-00103
cAMP Hunter™ Follitropin Alfa Bioassay Kit

/products/assay/follitropin-alfa-bioassay-kit-95-0119y2-00104
Gene Symbol
KINOME scan Gene Symbol td:first-child { background-color:#FFFFCC; } KINOMEscan Gene Symbol Entrez Gene Symbol Accession Number AAK1 AAK1 NP_055726.3 ABL1(E255K)-phosphorylated ABL1 NP_005148.2 ABL1(F317I)...
/services/drug-discovery-development-services/kinase-profiling/kinomescan/gene-symbol 3/4/2016 8:11:57 PM
Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation andchemotaxis assays.
BACKGROUND AND PURPOSE: Investigators have suggested that the chemokine receptor CCR1 plays a role in multiple myeloma. Studies using antisense and neutralizing antibodies to CCR1 showed that down-regulation of the receptor altered disease progression in a mouse model...
/tools-resources/publications-references/publications/identifying-bias-in-ccr1-antagonists-using-radiola 8/13/2015 3:54:33 PM
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
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/tools-resources/publications-references/publications/screening-β-arrestin-recruitment-for-the-identific 2/27/2013 11:38:37 PM
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