/products/proteins/14-481
/products/proteins/14-481m
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been ...
/target-data-sheets/kinase/pak2
2/12/2015 9:47:46 PM
PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell in...
/target-data-sheets/kinase/pkn2
2/12/2015 9:48:02 PM
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 ...
/target-data-sheets/kinase/pak4
2/12/2015 9:47:47 PM
KINOME scan Gene Symbol td:first-child { background-color:#FFFFCC; } KINOMEscan Gene Symbol Entrez Gene Symbol Accession Number AAK1 AAK1 NP_055726.3 ABL1(E255K)-phosphorylated ABL1 NP_005148.2 ABL1(F317I)...
/services/drug-discovery-development-services/kinase-profiling/kinomescan/gene-symbol
3/4/2016 8:11:57 PM
Find a Product "Cysteinome" Assay Portfolio - potential targets for the rational development of irreversible inhibitors In a recent publication ( Liu Q., et.al . 2013 ) they identify almost 200 kinases that contain a reactive nucleophilic cysteine residue near the ATP bin...
/targets/kinase-target-biology/cysteine-kinases
10/10/2014 5:14:34 PM