This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation....
/target-data-sheets/kinase/trkb
2/12/2015 9:45:59 PM
/products/proteins/14-507
/products/proteins/14-507m
/products/cell-line/u2os-trkb-functional-assay-93-0463c3
Strong genetic data link the Tyrosine kinase receptor B (TrkB) and its major endogenous ligand brain-derived neurotrophic factor (BDNF) to the regulation of energy homeostasis, with loss-of-function mutations in either gene causing severe obesity in both mice and humans. It h...
/tools-resources/publications-references/publications/activation-of-trkb-with-tam-163-results-in-opposit
7/5/2017 11:06:41 PM
Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin-related kinase B (TrkB), have emerged as key regulators of brain plasticity and represent disease-modifying targets for several brain disorders, including Alzheimer's disease and major depressive disorder....
/tools-resources/publications-references/publications/multiplex-quantitative-assays-indicate-a-need
11/17/2017 7:32:05 PM
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation....
/target-data-sheets/kinase/trkb-p75
2/12/2015 9:45:59 PM
/products/assay/trkb-functional-assay-93-0463e3cp16m
/products/assay/trkb-functional-assay-93-0463e3cp16l
Technology Slides Customer Facing Webinars Biologics (Large Molecules) Training Webinars Dimerization Assays - R&D Presented by Jane Lamerdin, Jane does a deeper dive on the dimerization assays. Presented Jul. 3, 2014. Downloads available: MP4 file | WebEx f...
/marketing/secured-rights/welcome-to-discoverx-university/biologics
6/4/2014 7:45:43 PM
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