/products/proteins/14-959
/products/proteins/14-959m
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as ...
/target-data-sheets/kinase/ulk1
2/12/2015 9:48:35 PM
Drug efficacy and cellular target engagement studies have traditionally been monitored by evaluation of downstream cellular responses, such as detection of substrate phosphorylation by upstream kinases for example. Alternative biochemical techniques, based on measuring the th...
/tools-resources/document-resource-library/documents/utilisation-of-the-incell-hunter-target-engagement
9/9/2015 8:55:18 PM
KINOME scan Gene Symbol td:first-child { background-color:#FFFFCC; } KINOMEscan Gene Symbol Entrez Gene Symbol Accession Number AAK1 AAK1 NP_055726.3 ABL1(E255K)-phosphorylated ABL1 NP_005148.2 ABL1(F317I)...
/services/drug-discovery-development-services/kinase-profiling/kinomescan/gene-symbol
3/4/2016 8:11:57 PM
Find a Product "Cysteinome" Assay Portfolio - potential targets for the rational development of irreversible inhibitors In a recent publication ( Liu Q., et.al . 2013 ) they identify almost 200 kinases that contain a reactive nucleophilic cysteine residue near the ATP bin...
/targets/kinase-target-biology/cysteine-kinases
10/10/2014 5:14:34 PM