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v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES)
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogen...
/target-data-sheets/kinase/yes 2/12/2015 9:48:40 PM
Reference Compound Data
Contact a Specialist Reference Data & Interaction Maps for Kinase Inhibitor Compounds KINOME scan ® data has been widely published and referenced in leading publications and support many landmark kinase inhibitors papers.  These data represent among the most extensive co...
/services/drug-discovery-development-services/kinase-profiling/reference-compound-data 9/27/2012 3:39:09 PM
Available GPCR Service Assays
Panel Run Schedule Below is a list of all the GPCR assays and readouts that DiscoverX offers. Request a Quote       Allostery White Paper   Overview of GPCR scan ® Panels & Services Services Assays Pre-configured Panel Customizable? Single Assay Technolog...
/services/drug-discovery-development-services/gpcr-screening-profiling-services/gpcrscan-gpcr-profiling 8/14/2012 5:31:37 PM
BROMOscan
Platform Benefits BROMO scan is a novel industry leading platform for identifying small molecule bromodomain inhibitors. Bromodomains are epigenetic “reader” proteins that have emerged as an important new druggable target class in small molecule inhibitor drug discovery with...
/services/drug-discovery-development-services/epigenetic-profiling/bromoscan 1/8/2014 6:36:13 PM
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 (YES)
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogen...
/target-data-sheets/kinase/yes1 2/12/2015 9:46:03 PM
KINOMEscan
Platform Benefits The KINOME scan platform employs a novel and proprietary active site-directed competition binding assay to quantitatively measure interactions between test compounds and more than 480 kinase assays including clinically relevant mutants, lipid, atypical, and...
/services/drug-discovery-development-services/kinase-profiling/kinomescan 8/14/2012 5:33:40 PM
EPIscan
Platform Benefits New!   EPI scan screening and profiling services provides a rapidly growing menu of cell-based bromodomain and histone methyltransferase (HMT) assays. Based on the novel InCELL Hunter™ technology, these assays provide a direct measure of compound permeabi...
/services/drug-discovery-development-services/epigenetic-profiling/episcan 8/6/2013 6:52:23 PM
Pathway Profiling
Platform Benefits LeadHunter ®  Discovery Services provides you access to a comprehensive collection of cell-based pathway indicator assays designed to detect activation or inhibition of complex signal transduction pathways in response to compound treatment. Based on the pro...
/services/drug-discovery-development-services/pathscan-pathway-profiling 8/14/2012 5:32:20 PM
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