The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressiv...
/target-data-sheets/kinase/mtor
2/12/2015 9:47:37 PM
/products/proteins/14-770
/products/proteins/14-770m
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as ...
/target-data-sheets/kinase/ulk1
2/12/2015 9:48:35 PM
/products/proteins/15-005
/products/proteins/15-005m
2/16/2023 11:39:59 AM
Thymic stromal lymphopoietin (TSLP) is a cytokine released by human lung epithelium in response to external insult. Considered as a master switch in T helper 2 lymphocyte (Th2) mediated responses, TSLP is believed to play a key role in allergic diseases including asthma. The ...
/tools-resources/publications-references/publications/phenotypic-strategy-inhibit-tslp-lung-epitheli-(1)
1/24/2020 10:29:02 AM
/products/proteins/14-772
/products/proteins/14-772m
/products/reagent/wortmannin-92-1095
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