Targets / Checkpoint / PD-L2
Contact a Specialist

Programmed cell death 1 ligand 2 (PDL2)

Target Class
Checkpoint Receptor
Family
T cell receptor ligand (inhibitory)
Official Symbol
PD-L2
Species
Human
Accession Number
NM_025239.3
Alias Names
CD274; B7-H; PDCD1L1; PDCD1LG1; PDL1
Background
Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene.PDCD1LG2 has also been designated as CD273 and has been speculated to play a major role in suppressing the immune system, with possible roles in cancer-induced immune suppression. This receptor is known to bind to and activate the PD-1 receptor.
+ Show More

Solution Portfolio

Related Group Members: T cell receptor ligand (inhibitory)
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Cell Lines
Assay Measures Background Species Cell Line
Ligand Presenting U2OS Human 93-1076C3
LeadHunter Screening & Profiling Services
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan