Cholecystokinin B receptor (CCK2)
- Target Class
- GPCR
- Family
- Cholecystokinin
- Official Symbol
- CCKBR
- Species
- Human
- Accession Number
- AY322551
- Alias Names
- CCK-B; CCK-B receptor; CCK-BR; CCK2 receptor; CCK2-R; CCK2R; GASR; cholecystokinin B receptor; cholecystokinin-2 receptor; gastrin receptor; gastrin/cholecystokinin type B receptor
- Background
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Cholecystokinin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
CHO-K1 |
Human |
93-0191C2 |
Internalization |
U2OS |
Human |
93-0708C3 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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