Endothelin receptor type A (ETA)
- Target Class
- GPCR
- Family
- Endothelin
- Official Symbol
- EDNRA
- Species
- Human
- Accession Number
- AY275462
- Alias Names
- ET-A; ETA; ETA-R; ETAR; ETRA; G protein-coupled receptor; endothelin receptor subtype A; endothelin receptor type A; endothelin-1 receptor; endothelin-1-specific receptor; hET-AR
- Background
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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Solution Portfolio
Related Family Members:
Endothelin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0257C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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