G-protein coupled receptor 119 (GPR119)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR119
- Species
- Human
- Accession Number
- NM_178471
- Alias Names
- G protein-coupled receptor 119; G-protein coupled receptor 119; G-protein coupled receptor 2; GPCR2; glucose-dependent insulinotropic receptor
- Background
This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]
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Solution Portfolio
Related Family Members:
Class A Orphan
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
Assay Readout |
Background |
Species |
Cell Line |
β-Arrestin |
HEK 293 |
Human |
93-0356C1 |
β-Arrestin |
U2OS |
Human |
93-0356C3 |
KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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