G-protein coupled receptor 50 (GPR50)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- GPR50
- Species
- Human
- Accession Number
- NM_004224
- Alias Names
- G protein-coupled receptor 50; H9; Mel1c; melatonin-related receptor
- Background
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
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Solution Portfolio
Related Family Members:
Class A Orphan
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0648C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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