Chemokine (C-X-C motif) receptor 2 (mCXCR2)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- mCXCR2
- Species
- Mouse
- Accession Number
- NM_009909
- Alias Names
- C-X-C chemokine receptor type 2; CD128; CDw128; CXC-R2; CXCR-2; Cmkar2; GRO/MGSA receptor; Gpcr16; IL-8 receptor alpha chain; IL-8R B; IL-8Rh; IL-8rb; IL8RA; Il8rb; chemokine (C-X-C motif) receptor 2; chemokine (C-X-C) receptor 2; high affinity interleukin-8 receptor B; interleukin 8 receptor, beta; interleukin-8 receptor type B; mIL-8RH
- Background
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
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Solution Portfolio
Related Family Members:
Chemokine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Mouse |
93-0513C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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