Chemokine (C motif) XC receptor 1 (XCR1)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- XCR1
- Species
- Human
- Accession Number
- NM_005283
- Alias Names
- CCXCR1; G protein-coupled receptor 5; G-protein coupled receptor 5; GPR5; XC chemokine receptor 1; chemokine (C motif) XC receptor 1; chemokine (C motif) receptor 1; chemokine XC receptor 1; lymphotactin receptor
- Background
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Chemokine
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TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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