ankyrin repeat and kinase domain containing 1 (ANKK1)

Target Class
Kinase
Family
TKL
Official Symbol
ANKK1
Entrez Gene ID
255239
Species
Human
Accession Number
NP_848605.1
Alias Names
PKK2; X-kinase; ankyrin repeat and kinase domain containing 1; ankyrin repeat and protein kinase domain-containing protein 1; protein kinase PKK2; sgK288; sugen kinase 288
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]
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Solution Portfolio

Related Group Members: TKL
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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