Targets / Kinase / IKK-alpha

conserved helix-loop-helix ubiquitous kinase (IKK-alpha)

Target Class
Kinase
Family
Other
Official Symbol
CHUK
Entrez Gene ID
1147
Species
Human
Accession Number
NP_001269.3
Alias Names
I-kappa-B kinase 1; I-kappa-B kinase-alpha; IKBKA; IKK-a kinase; IKK-alpha; IKK1; IKKA; IkB kinase alpha subunit; NFKBIKA; Nuclear factor NFkappaB inhibitor kinase alpha; TCF-16; TCF16; conserved helix-loop-helix ubiquitous kinase; inhibitor of nuclear factor kappa-B kinase subunit alpha; transcription factor 16
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
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