Targets / Kinase / IKK-beta

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKK-beta)

Target Class
Kinase
Family
Other
Official Symbol
IKBKB
Entrez Gene ID
3551
Species
Human
Accession Number
NP_001547.1
Alias Names
I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-B; IKK-beta; IKK2; IKKB; NFKBIKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of nuclear factor kappa-B kinase subunit beta; nuclear factor NF-kappa-B inhibitor kinase beta
Background
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]
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