Targets / Kinase / LZK

mitogen-activated protein kinase kinase kinase 13 (LZK)

Target Class
Kinase
Family
TKL
Official Symbol
MAP3K13
Entrez Gene ID
9175
Species
Human
Accession Number
NP_004712.1
Alias Names
LZK; MEKK13; MLK; leucine zipper-bearing kinase; mitogen-activated protein kinase kinase kinase 13; mixed lineage kinase
Background
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]
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Related Group Members: TKL
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