Find a Product

c-mer proto-oncogene tyrosine kinase (MERTK)

Target Class
Kinase
Family
TK
Official Symbol
MERTK
Entrez Gene ID
10461
Species
Human
Accession Number
AAB60430.1
Alias Names
MER; MER receptor tyrosine kinase; RP38; STK kinase; c-mer; c-mer proto-oncogene tyrosine kinase; proto-oncogene c-Mer; receptor tyrosine kinase MerTK; tyrosine-protein kinase Mer
Background
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
+ Show More


Solution Portfolio

Related Group Members: TK
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available