Targets / Kinase / MKNK1

MAP kinase interacting serine/threonine kinase 1 (MKNK1)

Target Class
Kinase
Family
CAMK
Official Symbol
MKNK1
Entrez Gene ID
8569
Species
Human
Accession Number
NP_001129025.1
Alias Names
MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MNK1
Background
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
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Related Group Members: CAMK
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