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NIMA (never in mitosis gene a)-related kinase 1 (NEK1)

Target Class
Kinase
Family
Other
Official Symbol
NEK1
Entrez Gene ID
4750
Species
Human
Accession Number
NP_036356.1
Alias Names
NIMA (never in mitosis gene a)-related kinase 1; NY-REN-55; SRPS2; never in mitosis A-related kinase 1; nimA-related protein kinase 1; protein-serine/threonine kinase; renal carcinoma antigen NY-REN-55; serine/threonine-protein kinase Nek1
Background
The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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