Targets / Kinase / NEK2

NIMA (never in mitosis gene a)-related kinase 2 (NEK2)

Target Class
Kinase
Family
Other
Official Symbol
NEK2
Entrez Gene ID
4751
Species
Human
Accession Number
NP_002488.1
Alias Names
HsPK21; NEK2A; NIMA (never in mitosis gene a)-related kinase 2; NLK1; nimA-like protein kinase 1; nimA-related protein kinase 2; serine/threonine-protein kinase Nek2
Background
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]
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