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phosphoinositide-3-kinase, catalytic, beta polypeptide (PIK3CB)

Target Class
Kinase
Family
Lipid
Official Symbol
PIK3CB
Entrez Gene ID
5291
Species
Human
Accession Number
NP_006210.1
Alias Names
P110BETA; PI3-kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K-beta; PI3KBETA; PIK3C1; PtdIns-3-kinase p110; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphoinositide-3-kinase, catalytic, beta polypeptide; ptdIns-3-kinase subunit beta; ptdIns-3-kinase subunit p110-beta
Background
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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