Targets / Kinase / PLK4

polo-like kinase 4 (PLK4)

Target Class
Kinase
Family
Other
Official Symbol
PLK4
Entrez Gene ID
10733
Species
Human
Accession Number
NP_055079.2
Alias Names
PLK-4; SAK; STK18; Snk akin kinase; polo-like kinase 4; polo-like kinase 4 (Drosophila); serine/threonine kinase 18; serine/threonine protein kinase SAK; serine/threonine-protein kinase 18; serine/threonine-protein kinase PLK4; serine/threonine-protein kinase Sak
Background
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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