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c-ros oncogene 1 , receptor tyrosine kinase (ROS1)

Target Class
Kinase
Family
TK
Official Symbol
ROS1
Entrez Gene ID
6098
Species
Human
Accession Number
NP_002935.2
Alias Names
MCF3; ROS; c-Ros receptor tyrosine kinase; c-ros oncogene 1 , receptor tyrosine kinase; c-ros-1; proto-oncogene c-Ros; proto-oncogene c-Ros-1; proto-oncogene tyrosine-protein kinase ROS; receptor tyrosine kinase c-ros oncogene 1; transmembrane tyrosine-specific protein kinase; v-ros UR2 sarcoma virus oncogene homolog 1; v-ros UR2 sarcoma virus oncogene homolog 1 (avian); v-ros avian UR2 sarcoma virus oncogene homolog 1
Background
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
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