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serine/threonine kinase 16 (STK16)

Target Class
Kinase
Family
Other
Official Symbol
STK16
Entrez Gene ID
8576
Species
Human
Accession Number
CAA06700.1
Alias Names
KRCT; MPSK; PKL12; TGF-beta-stimulated factor 1; TSF-1; TSF1; hPSK; myristoylated and palmitoylated serine/threonine-protein kinase; protein kinase PKL12; protein kinase expressed in day 12 fetal liver; serine/threonine kinase 16; serine/threonine-protein kinase 16; tyrosine-protein kinase STK16
Background
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
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Solution Portfolio

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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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