Targets / Kinase / TESK1

testis-specific kinase 1 (TESK1)

Target Class
Kinase
Family
TKL
Official Symbol
TESK1
Entrez Gene ID
7016
Species
Human
Accession Number
NP_006276.2
Alias Names
dual specificity testis-specific protein kinase 1; testicular protein kinase 1; testis-specific kinase 1
Background
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. [provided by RefSeq, Jul 2008]
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Related Group Members: TKL
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