tousled-like kinase 1 (TLK1)

Target Class
Kinase
Family
Other
Official Symbol
TLK1
Entrez Gene ID
9874
Species
Human
Accession Number
NP_036422.3
Alias Names
PKU-beta; SNARE protein kinase SNAK; serine threonine protein kinase; serine/threonine-protein kinase tousled-like 1; tousled-like kinase 1
Background
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
+ Show More


Solution Portfolio

Related Group Members: Other
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available