Targets / Kinase / WNK1

WNK lysine deficient protein kinase 1 (WNK1)

Target Class
Kinase
Family
Other
Official Symbol
WNK1
Entrez Gene ID
65125
Species
Human
Accession Number
NP_061852.3
Alias Names
HSAN2; HSN2; KDP; PRKWNK1; PSK; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; erythrocyte 65 kDa protein; hereditary sensory neuropathy, type II; p65; prostate-derived sterile 20-like kinase; protein kinase with no lysine 1; protein kinase, lysine deficient 1; serine/threonine-protein kinase WNK1
Background
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]
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