Targets / Kinase / WNK3

WNK lysine deficient protein kinase 3 (WNK3)

Target Class
Kinase
Family
Other
Official Symbol
WNK3
Entrez Gene ID
65267
Species
Human
Accession Number
NP_065973.2
Alias Names
PRKWNK3; WNK lysine deficient protein kinase 3; protein kinase with no lysine 3; protein kinase, lysine deficient 3; serine/threonine-protein kinase WNK3
Background
This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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