Kinase Targets

Empowering Your Kinase Discovery by Measuring the Right Signaling Solution for the Right Question

Eurofins DiscoverX enables kinase drug discovery with product solutions for the questions you need answered. Cellular assays and recombinant kinases were developed to be used at all stages of drug discovery, and are ideal for identifying highly potent and selective kinase inhibitors. Products cover the human Kinome so you can always find a solution for your kinase target.

Kinase Solutions

Learn more about the updated Cell Culture and Handling Procedure in the new Technical Bulletin.

View By Kinase Group

AGC AGC AKT1 AKT2 AKT3 CIT DMPK DMPK2 GRK1 GRK2 GRK3 GRK4 GRK7 LATS1 LATS2 MAST1 MRCKA MRCKB NDR1 NDR2 PDPK1 PKAC-alpha PKAC-alpha(L206R) PKAC-beta PKN1 PKN2 PRKCD PRKCE PRKCH PRKCI PRKCQ PRKG1 PRKG2 PRKX ROCK1 ROCK2 RPS6KA4(Kin.Dom.1-N-terminal) RPS6KA5(Kin.Dom.1-N-terminal) RSK1(Kin.Dom.1-N-terminal) RSK2(Kin.Dom.1-N-terminal) RSK3(Kin.Dom.1-N-terminal) RSK4(Kin.Dom.1-N-terminal) S6K1 SGK SGK2 SGK3 YANK1 YANK2 YANK3	Atypical Atypical ADCK3 ADCK4 MTOR RIOK1 RIOK2 RIOK3 TRPM6	CAMK CAMK AMPK-alpha1 AMPK-alpha2 ARK5 BRSK1 BRSK2 CAMK1 CAMK1B CAMK1D CAMK1G CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CASK CHEK1 CHEK2 DAPK1 DAPK2 DAPK3 DCAMKL1 DCAMKL2 DCAMKL3 DRAK1 DRAK2 HUNK LKB1 MAPKAPK2 MAPKAPK5 MARK1 MARK2 MARK3 MARK4 MELK MKNK1 MKNK2 MLCK MYLK MYLK2 MYLK4 NIM1 PASK PHKG1 PHKG2 PIM2 PIM3 PRKD1 PRKD2 PRKD3 QSK RPS6KA4(Kin.Dom.2-C-terminal) RPS6KA5(Kin.Dom.2-C-terminal) RSK1(Kin.Dom.2-C-terminal) RSK2(Kin.Dom.2-C-terminal) RSK3(Kin.Dom.2-C-terminal) RSK4(Kin.Dom.2-C-terminal) SIK SIK2 SNARK SNRK STK33 TSSK1B TSSK3	CDC-like Kinase CDC-like Kinase CLK1 CLK2	CK1 CK1 CSNK1A1 CSNK1A1L CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 VRK2
CMGC CMGC CDC2L1 CDC2L2 CDC2L5 CDK1 CDK10 CDK11 CDK12 CDK2 CDK20 CDK3 CDK4 CDK4-cyclinD1 CDK4-cyclinD1(F93L) CDK4-cyclinD3 CDK5 CDK6 CDK7 CDK8 CDK9 CDKL1 CDKL2 CDKL3 CDKL5 CLK3 CLK4 DYRK1A DYRK1B DYRK2 ERK1 ERK1(Q122L) ERK2 ERK3 ERK4 ERK5 ERK8 GSK3A GSK3B HIPK1 HIPK2 HIPK3 HIPK4 ICK JNK1 JNK2 JNK3 MAK NLK p38-alpha p38-beta p38-delta p38-gamma PCTK1 PCTK2 PCTK3 PFTAIRE2 PFTK1 PRP4 SRPK1 SRPK2 SRPK3	Cytosolic tyrosine kinase Cytosolic tyrosine kinase BLK BTK CSF3R-JAK1 FGR GHR-JAK1 GHR-JAK2 HCK JAK3 PRLR-JAK1 PRLR-JAK2 SYK TYK2 YES1	Extracellular signal-regulated kinase Extracellular signal-regulated kinase MEK1	Lipid Lipid PIK3C2B PIK3C2G PIK3CA PIK3CA(C420R) PIK3CA(E542K) PIK3CA(E545A) PIK3CA(E545K) PIK3CA(H1047L) PIK3CA(H1047Y) PIK3CA(I800L) PIK3CA(M1043I) PIK3CA(Q546K) PIK3CB PIK3CD PIK3CG PIK4CB PIKFYVE PIP5K1A PIP5K1C PIP5K2B PIP5K2C VPS34	Non-receptor tyrosine kinase Non-receptor tyrosine kinase ABL1
Other Other AAK1 AURKA AURKB AURKC BIKE BUB1 CAMKK1 CAMKK2 CSNK2A1 CSNK2A2 EIF2AK1 ERN1 GAK GCN2(Kin.Dom.2,S808G) HASPIN IKK-alpha IKK-beta IKK-epsilon NEK1 NEK10 NEK11 NEK2 NEK3 NEK4 NEK5 NEK6 NEK7 NEK9 PKMYT1 PLK1 PLK2 PLK3 PLK4 PRKR RIPK5 SBK1 SgK110 STK16 STK35 STK36 TBK1 TLK1 TLK2 TTK ULK1 ULK2 ULK3 WEE1 WEE2 WNK1 WNK2 WNK3 WNK4	Pathogen Pathogen PFCDPK1(P.falciparum) PFPK5(P.falciparum) PKNB(M.tuberculosis)	Phosphoinositide kinase Phosphoinositide kinase PI3Kδ	Protein Kinase Protein Kinase CSNK1D	Protein Tyrosine Kinase Protein Tyrosine Kinase PYK2
Receptor Tyrosine Kinase Receptor Tyrosine Kinase AXL cINSRa cINSRb c-KIT c-MET/c-MET c-Ret-GFRα1 c-Ret-GFRα2 CSF1R CSF1R/CSF1R DDR1 EGFR/EGFR EGFR/ErbB2 EGFR/ErbB3 EphA4 EphA5 EphA7 EphB1 EphB2 EphB3 EphB4 ErbB1 ErbB2/ErbB3 ErbB2/ErbB4 ErbB2-ErbB3 ErbB4 ErbB4/ErbB4 FGFR1 FGFR1-α-Klotho FGFR1-β-Klotho FGFR2 FGFR3(G380R)/FGFR3(G380R) FGFR3/FGFR3 FGFR4 FGFR4-α-Klotho FGFR4-β-Klotho FLT3 FLT4 IGF1R INSRa INSRb KDR KDR/KDR mINSRa mINSRb PDGFRa PDGFRb rhTrkA-rhP75 RIPK2 rTrkA-rP75 Tie2 TrkA TrkA-P75 TrkB TrkB-P75 TrkC TrkC-P75	Ser/Thr Kinase Ser/Thr Kinase ACVR1B/BMPR2 ACVR1C/ACVR2 ACVR1C/ACVR2B ACVR2/ACVR1 ACVRL1/ACVR2 ACVRL1/ACVR2B ACVRL1/BMPR2 BMPR1A/ACVR2 BMPR1A/ACVR2B BMPR1A/BMPR2 BMPR1B/ACVR2 BMPR1B/ACVR2B BMPR1B/BMPR2 PIM1 RIPK1 RIPK3 SIK1 TGFBR1/ACVR2 TGFBR1/ACVR2B TGFBR1/TGFBR2 TGFBR1/TGFBR2/ENG	STE STE ASK1 ASK2 HPK1 LOK MAP3K1 MAP3K15 MAP3K2 MAP3K3 MAP3K4 MAP4K2 MAP4K3 MAP4K4 MAP4K5 MEK2 MEK3 MEK4 MEK5 MEK6 MINK MKK7 MST1 MST2 MST3 MST4 MYO3A MYO3B NIK OSR1 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 SLK STK39 TAOK1 TAOK2 TAOK3 TNIK YSK1 YSK4	TK TK ABL1(E255K)-phosphorylated ABL1(F317I)-nonphosphorylated ABL1(F317I)-phosphorylated ABL1(F317L)-nonphosphorylated ABL1(F317L)-phosphorylated ABL1(H396P)-nonphosphorylated ABL1(H396P)-phosphorylated ABL1(M351T)-phosphorylated ABL1(Q252H)-nonphosphorylated ABL1(Q252H)-phosphorylated ABL1(T315I)-nonphosphorylated ABL1(T315I)-phosphorylated ABL1(Y253F)-phosphorylated ABL1-nonphosphorylated ABL1-phosphorylated ABL2 ALK ALK(1151Tins) ALK(C1156Y) ALK(F1174L) ALK(L1196M) BMX BRK CSF1R-autoinhibited CSK CTK DDR2(T654M) EGFR EGFR(E746-A750del) EGFR(G719C) EGFR(G719S) EGFR(L747-E749del, A750P) EGFR(L747-S752del, P753S) EGFR(L747-T751del,Sins) EGFR(L858R) EGFR(L858R,T790M) EGFR(L861Q) EGFR(S752-I759del) EGFR(T790M) EPHA1 EPHA2 EPHA3 EPHA6 EPHA8 EPHB6 ERBB2 ERBB3 FAK FER FES FGFR2(N550K) FGFR3 FGFR3(G697C) FGFR3(K650E) FGFR3(V555M) FGFR4 FLT1 FLT3(D835H) FLT3(D835V) FLT3(D835Y) FLT3(ITD) FLT3(ITD,D835V) FLT3(ITD,F691L) FLT3(K663Q) FLT3(N841I) FLT3(R834Q) FLT3-autoinhibited FRK FYN INSR INSRR ITK JAK1(JH1domain-catalytic) JAK1(JH2domain-pseudokinase) JAK2(JH1domain-catalytic) JAK3(JH1domain-catalytic) KIT KIT(A829P) KIT(D816H) KIT(D816V) KIT(L576P) KIT(V559D) KIT(V559D,T670I) KIT(V559D,V654A) KIT-autoinhibited LCK LTK LYN MERTK MET MET(M1250T) MET(Y1235D) MST1R MUSK RET RET(A883F) RET(M918T) RET(V804E) RET(V804L) RET(V804M) ROS1 SRC SRMS TEC TIE1 TIE2 TNK1 TNK2 TXK TYK2(JH1domain-catalytic) TYK2(JH2domain-pseudokinase) TYRO3 VEGFR2 YES ZAP70	TKL TKL ACVR1 ACVR1B ACVR2A ACVR2B ACVRL1 ANKK1 BMPR1A BMPR1B BMPR2 BRAF BRAF(V600E) DLK IRAK1 IRAK2 IRAK3 IRAK4 LIMK1 LIMK2 LRRK2 LRRK2(G2019S) LZK MLK1 MLK2 MLK3 MLKL MLKL(full-length) RAF1 RIPK1 RIPK3 RIPK4 TAK1 TESK1 TGFBR1 TGFBR2 TNNI3K ZAK

Cell Lines

Explore our growing panel of target-specific, stable kinase cell lines for measuring the activity of receptor tyrosine kinases (RTKs) and non-receptor cytosolic tyrosine kinases (CTKs) as well as binding to internal kinases.
Learn how InCELL Compound-Target Engagement works >
Learn how PathHunter Kinase assays work >

Assay Ready Kits

Assay Ready products are complete, ready-to-use kits that include all the cells and reagents to measure kinase activation or binding in live cells. Free yourself from lengthy cell culture and expensive instrumentation.
Learn about Assay Ready eXpress™ Kits >

Enzymes

Eurofins DiscoverX has applied its protein production and purification expertise to provide a large portfolio of kinases and phosphotases used in our kinase screening and profiling services for use in your lab.

Learn about all our available Proteins >

Kinase Proteins

Biochemical Assays

Study active kinases using our universal ADP accumulation assays. Explore inactive and active kinases with one of our highly quantitative, competitive binding platforms without using antibodies or kinase substrates.
Learn about ADP Accumulation assays >

ADP Quest™ & Hunter™ ADP Accumulation Assays

Cell Culture Kits, Reagents & Consumables

Performance you can trust! Get the highest quality data from your cell-based kinase assays in combination with our lab-certified PathHunter® cell culture media, tissue culture reagents and plates.

Ligands & Inhibitors

Designed to target a specific kinase receptor or pathway, our purified reference ligands and inhibitors are a convenient and cost-effective way to validate any stable Kinase cell line or assay-ready kit.

Inhibitors & Ligands

Detection Reagents

Get optimal assay performance using certified chemiluminescent or fluorescent PathHunter® and InCELL Detection Reagents that have been validated for use in both 96-well and 384-well microplate formats
How detection works >