[Gordon GPCR Research 2019] GPCR Allosteric Modulation: Another Shot on Goal

[Gordon GPCR Research 2019] GPCR Allosteric Modulation: Another Shot on Goal
File Name/Number:
Gordon GPCR Research 2019

Year:
2019

Although historically GPCRs have been a rich source of new drug molecules, the discovery of unique drug types for this target class has waned in the last 3 decades. In the same time frame, the emergence of functional screening and the appreciation of the allosteric nature of GPCRs has revitalized the field and led to an explosion of activity that has transformed GPCR discovery. Thus allosteric screening and development are seen as another shot on goal for many mined out and/or intractable GPCR targets.