Ligand Characterization of Mas-Related GPCR-X2 via Cell-Based Assays: Assessing the Regulation of Mast Cell Function and Implications in Safety Pharmacology

Ligand Characterization of Mas-Related GPCR-X2 via Cell-Based Assays: Assessing the Regulation of Mast Cell Function and Implications in Safety Pharmacology
Version:
21315

Year:
2022

 

An Application Note Assessing the Regulation of Mast Cell Function and its Implications in Safety Pharmacology.

MrgprX2 antagonism promotes fresh interest as an emerging therapeutic target for the treatment of pseudo-allergic reactions, and Eurofins DiscoverX qualified assays are ideal to support research programs centered on MrgprX2 activation and mast cell regulation.