CLK1, active

10 µg of active CLK1. N-terminal 6His-tagged recombinant, human CLK1 amino acids 130-end.

Catalog #: 14-920

$399.00$2,989.00


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Biological Information
Background Information:
CLK1 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
Target Class:
Kinase
Family:
CMGC Kinase
Accession Number:
NM_004071
Target Name:
CLK1
Target Aliases:
CLK1, CLK, STY
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-920x Datasheet

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