Biological Information | |
---|---|
Background Information: | RIPK1 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017] |
Target Class: | Kinase |
Family: | TK-Like Kinase |
Accession Number: | GenBank NM_003804.3 |
Target Name: | RIPK1 |
Target Aliases: | Receptor Interacting Serine/Threonine Kinase 1, Receptor (TNFRSF)-Interacting Serine-Threonine Kinase, Receptor-Interacting Serine/Threonine-Protein Kinase 1, Receptor-Interacting Protein Kinase 1, Serine/Threonine-Protein Kinase RI |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 1 year at -70°C |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
RIPK1, active
active RIPK1.C-terminal 6His-tagged, recombinant, human RIPK1 amino acids 8-322.
Datasheets
16-022x Datasheet
View Document