Arg, active

N-terminal 6His-tagged recombinant, murine Arg amino acids 27-end.

Catalog #: 14-460

$399.00$2,989.00


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Biological Information
Background Information:
The mammalian Abelson (Abl) family of non-receptor tyrosine kinases is comprised of c-Abl (ABL1) and Arg (Abl-related gene, ABL2), which are encoded by the Abl1 and Abl2 genes, respectively. Deregulation of the c-Abl and Arg tyrosine kinases can occur as a result of chromosomal translocation events that produce chimeric proteins associated with the development of human leukemias as well as gastric cancer invasion and progression. GenBank XM_136360. The recombinant protein also contains 2 residues which are in conflict with GenBank XM_136360. These are M982V, reported in GenBank NM_005158, NM_007314, M35296, and an A inserted at position 562, reported in GenBank U40827. The residue coordinates in the native sequence have been given.
Target Class:
Kinase
Accession Number:
NM_005158.2; NM_007314.1
Target Name:
Arg
Target Aliases:
ABL proto-oncogene 2, non-receptor tyrosine kinase, ABL2, Abelson-related, ABLL, ARG
Target Species:
Mouse
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-460x Datasheet

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