MRCKalpha, active

C-terminal 6His-tagged recombinant, human MRCKα amino acids 1-473.

Catalog #: 14-691

$399.00$2,989.00


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Biological Information
Background Information:
MRCKα Protein is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. GenBank NM_003607
Target Class:
Kinase
Accession Number:
NM_003607.3; NM_014826.4
Target Name:
MRCKα
Target Aliases:
CDC42BPA, DKFZp686L1738, PK428, DKFZp686P1738, KIAA0451, FLJ23347, MRCK, MRCKA
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-691x Datasheet

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