Biological Information

Background Information:

The Kinase Enzyme Activity Assay Kit is a biochemical assay for the measurement of kinase inhibitors. The kit uses the HitHunter® assay technology and has been optimized for BTK. All reagents are provided in the kit, including recombinant BTK (Eurofins #14-552), substrate, ATP, detection reagents and assay plates. The COA that accompanies the kit details the optimal reaction conditions for the detection of kinase inhibitors. The kit includes sufficient material to run reactions for two 384-well assay plates.

Target Class:

Kinase

Family:

TK

Sub Family:

Serine/threonine kinase

Protein Name:

BTK

Protein Aliases:

Bruton's tyrosine kinase

Accession Number:

NM_000061.1

UniProt Number:

Q06187

Gene Name:

BTK

Gene ID:

695

Gene Aliases:

ATK|XLA|PSCTK1

Target Species:

Human

Usage

Product Type:

Enzyme Activity Assay Kits

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Measures:

ADP Accumulation

Detection Method:

Fluorescence

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology

Additional Information

Brand: