Bmx, active

Background Information:

BMX (also called ETK, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase) is one of the non-receptor tyrosine kinases, located intracellularly. It is a Src homolog and contains an SH3 and SH2 domain upstream from the tyrosine kinase domain. Unlike other members of the BTK family kinases, which are mostly hemopoietic cell-specific, BMX is preferentially expressed in epithelial and endothelial cells of large arteries. Inhibitors of BMX may be useful in the treatment of atherosclerosis and cancer. GenBank NM_001721

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

BMX

Protein Aliases:

BTK-like on X chromosome

Accession Number:

NM_001721.4; NM_203281.1

UniProt Number:

P51813

Gene Name:

BMX

Gene ID:

660

Gene Aliases:

ETK|PSCTK3

Target Species:

Human