Biological Information
Background Information:
Anti-B-cell maturation antigen (BCMA) antibodies are a class of drugs used to treat relapsed or refractory multiple myeloma (a type of cancer of the bone marrow) for adult patients who have received at least four other medications including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulatory agent. The only drug that belongs to this class is “belantamab mafodotin,” a humanized IgG1κ monoclonal antibody that targets the BCMA conjugated with a cytotoxic agent, maleimidocaproyl monomethylauristatin-F (MMAF).
Target Class:
Signaling Pathway
Family:
Tumour Necrosis Factor (TNF)
Usage
Product Type:
Antibodies
Application:
Drug Discovery & Development
Storage Conditions:
4°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®