Biological Information
Background Information:
The cAMP Hunter™ GIP RA Bioassay Kit provides a robust, and highly sensitive functional, cell-based assay to monitor 3’-5’-cyclic adenosine monophosphate (cAMP) production in cells, as a result of ligand mediated activation of GIP receptor. The bioassay kit contains all the materials needed for a complete assay, including cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure assay reproducibility and faster implementation from characterization to QC lot-release. This bioassay has been optimized for a 96-well format. Note that control agonist for stimulating the cells, GIP (Gastric inhibitory peptide), may not be included in the kit, and may be purchased separately.
Target Class:
GPCR
Family:
Glucagon
Protein Name:
GIP
Protein Aliases:
Glucose-dependent insulinotropic polypeptide
Accession Number:
NM_004123.3
UniProt Number:
P09681
Gene Name:
GIP
Gene ID:
2695
Target Species:
Human
Cell Background:
CHO-K1
Usage
Product Type:
Bioassay Kits
Application:
Potency, Commercial Release & Stability
Storage Conditions:
Short term (<24 h): Store at -80°C; Long term (>24 h): Store in vapor phase of liquid nitrogen.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Measures:
cAMP Detection
Detection Method:
Chemiluminescence
Clinical Relevance
Therapeutic Area:
Metabolic Diseases
Additional Information
Brand:
cAMP Hunter™